Exploring Frontiers With Computational Power

Research @ WashU with David Spencer

By the numbers: RIS resources utilized 

  • 125TB active storage
  • 75TB of archive storage
  • Access to the general compute resource pool (5,000 CPU cores and 160 GPUs)
  • 28 CPU and 2 “DRAGEN” condo servers
  • Consumed 283,299 CPU core hours from 47,738 jobs

 Background: Basic biology of how mutations and acute myeloid leukemia contribute to the development of cancer. Specifically, genomics, how genes are regulated, and epigenetic modifications that regulate genes to understand processes in leukemia.

  • The translational focus is on the use of genomic technologies to advance patient testing specifically for mutations in cancer.

Relevance: Having a better understanding of how cancer works to predict how patients will respond to therapies and finding pathways that could target new therapies to improve patient outcomes.

  • If there is a way to improve the accuracy, speed, and precision of diagnostic testing using new technology there is always relevance in research. 

Objective: Improve clinical management and care of cancer patients’ outcomes and lives while better understanding basic science.

Measured success: Done through discoveries that are published in papers and the development of new innovations to test patients that can be used for clinical practice.