PacBio SMRT Link is the software suite Pacific Biosciences (PacBio) provides for managing, analyzing, and interpreting data generated by its Single-Molecule Real-Time (SMRT) sequencing technology. SMRT Link is a vital tool for users of PacBio’s sequencing platforms, enabling them to process raw sequencing data, manage sequencing runs, perform data analysis, and visualize results. It supports various applications such as genome assembly, variant detection, and transcriptome analysis.

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Key Features

  • Sample Setup – Calculate binding and annealing reactions for preparing DNA libraries for use on all PacBio HiFi sequencing systems.
  • Runs – View information about sequencing runs, monitor run progress, and create run designs.
  • Instruments – View information about instruments connected to SMRT Link, including sequencing status, remaining run time, and pre-load availability for the next run.
  • Data Management – Create projects and data sets; generate QC reports for data sets; view, import, or delete sequence, reference, and barcode files.
  • SMRT Analysis – Perform secondary analysis on the basecalled data, including sequence alignment, variant detection, structural variant calling, and RNA analysis.